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QS 11

CAS No. 944328-88-5

QS 11 ( QS11; QS-11; QS 11 )

Catalog No. M17682 CAS No. 944328-88-5

QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 78 In Stock
10MG 141 In Stock
25MG 321 In Stock
50MG 484 In Stock
100MG 700 In Stock
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Biological Information

  • Product Name
    QS 11
  • Note
    Research use only, not for human use.
  • Brief Description
    QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor.
  • Description
    QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
  • Synonyms
    QS11; QS-11; QS 11
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    ARFGAP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    944328-88-5
  • Formula Weight
    567.7
  • Molecular Formula
    C36H33N5O2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 100 mg/mL 176.16 mM; H2O : < 0.1 mg/mL
  • SMILES
    OC[C@H](Cc1ccccc1)Nc1c2c(n(Cc3ccc(c4ccccc4)cc3)cn2)nc(Oc2ccc3CCCc3c2)n1
  • Chemical Name
    (2S)-2-[[2-(2,3-Dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]purin-6-yl]amino]-3-phenylpropan-1-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Emre N., et al. A chemical approach to stem cell biology. Curr Opin Chem Biol. 2007 Jun;11(3):252-8.
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