QS 11

CAS No. 944328-88-5

QS 11 ( QS11; QS-11; QS 11 )

Catalog No. M17682 CAS No. 944328-88-5

QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 45 In Stock
5MG 78 In Stock
10MG 141 In Stock
25MG 321 In Stock
50MG 484 In Stock
100MG 700 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    QS 11
  • Note
    Research use only, not for human use.
  • Brief Description
    QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor.
  • Description
    QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
  • Synonyms
    QS11; QS-11; QS 11
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    ARFGAP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    944328-88-5
  • Formula Weight
    567.7
  • Molecular Formula
    C36H33N5O2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 100 mg/mL 176.16 mM; H2O : < 0.1 mg/mL
  • SMILES
    OC[C@H](Cc1ccccc1)Nc1c2c(n(Cc3ccc(c4ccccc4)cc3)cn2)nc(Oc2ccc3CCCc3c2)n1
  • Chemical Name
    (2S)-2-[[2-(2,3-Dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]purin-6-yl]amino]-3-phenylpropan-1-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Emre N., et al. A chemical approach to stem cell biology. Curr Opin Chem Biol. 2007 Jun;11(3):252-8.
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